GameRant takes a look at who V should side with in
the I Walk the Line mission. Here is a snip;
Regardless of what the player chooses, be sure to grab the Bully mod behind the NetWatch Agent in this room before leaving. Both choices have a fair share of moral ambiguity and consequences, but in terms of gameplay, it seems like siding with the Voodoo Boys is the best choice here. Players worried about a difficult fight against multiple enemies later down the line should definitely not choose to anger the Voodoo Boys, since taking down the Netwatch agent is pretty easy.
That said, from V's perspective, it is definitely in their best interest to take the NetWatch agent up on their offer, as this will save a lot of pain from the malware. Moreover, some players could argue that siding with NetWatch is the right choice considering how the Voodoo Boys treated Evelyn Parker and contributed to her unfortunate fate.